Sunday, March 13, 2016

Week 10 Blog #2

Blog #2:
Week 10 March 7-13
Sunday, March 13, 2016
2p-10p 8 Hours Interned

Objective #2:
2. Will verbally demonstrate knowledge of tests included in a CMP and CBC/diff including abnormalities, what disease process they might indicate and possible signs and symptoms that a patient might demonstrate given these values.

So as indicated in my last post, a CBC has 3 main blood types being evaluated. Red blood cells, white blood cells, and platelets. But of those 3 categories, there are subdivisions that are evaluated, resulting in a total of 16 components to be evaluated. Below is a brief description of each of these components.

Red Blood Cells
- The cells that transport oxygen throughout the body
- Red Blood Cell Count is the total number of red blood cells in a person's sample of blood.
1. Hemoglobin (Hb) - Measures the total amount of the oxygen-carrying protein in the blood, which generally reflects the number of red blood cells in the blood.
2. Hematocrit (Hct) - measures the percentage of a person's total blood volume that consists of red blood cells.
3. Mean Corpuscular Volume (MCV) - A measurement of the average size of the red blood cell.
4. Mean Corpuscular Hemoglobin (MCH) - A calculation of the average amount of hemoglobin inside a red blood cell. 
5. Mean Corpuscular Hemoglobin Concentration (MCHC) - A calculation of the average concentration of hemoglobin inside a single red blood cell.
6. Red Blood Cell Distribution Width (RDW) - A calculation of the variation in the size of red blood cells.
7. Reticulocytes (not always done, but will still talk about it) - A measurement of the absolute count or percentage of young red blood cells in the blood.

White Blood Cells
- The cells that are part of the body's defense system against infections and cancer. Play a role in allergies and inflammation.
- White Blood Cell Count is the total number of white blood cells in a person's sample of blood.
8. White Blood Cell Differential (Diff) - May or may not be included as part of the panel or test. But if is, identifies and counts the number of various types of white blood cells present. There are 5 subtypes: neutrophils, lymphocytes, monocytes, eosinophils, and basophils.
9. Absolute Neutrophil Count (Neu, PMN, polys) - A measurement of the amount of neutrophils in the blood.
10. Absolute Lymphocyte Count (Lymph) - A measurement of lymphocytes in the blood.
11. Absolute Monocyte Count (Mono) - A number of monocytes in the blood.
12. Absolute Eosinophil Count (Eos) - A number of eosinophils in the blood.
13. Absolute Basophil Count (Baso) - A number of basophils in the blood.

** Keep in mind the functions of white blood cells. They are activated during innate and adaptive immunity or primarily when an infection occurs. An increased value of any WBC indicates some type of pathogenic invasion. Each of the WBC's listed above will be present when an infection is present, and which one is more numerous, can help indicate the type of infection.

Platelets
- Cell fragments that are vital for normal blood clotting.
14. Platelet Count (Plt) - The number of platelets in a person's sample of blood.
15. Mean Platelet Volume (MPV) - May be reported with a CBC. The calculation of the average size of platelets.
16. Platelet Distribution Width (PDW, not always reported, but will still talk about) - May be reported with a CBC. Reflects how uniform platelets are in size.

I will explain later what the normal range of these values are, abnormal values, the disease process that may be related to the abnormal value, and possibly signs and symptoms an individual would show related to the abnormal values.

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